PathSensors Biodefense & Building Protection

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Building Protection

Incorporating CANARY® technology, the BioFlash Pathogen Identifier provides rapid, sensitive and specific identification of biothreat agents (bacteria, viruses and toxins) from aerosol samples. The BioFlash can be integrated into a suite of CBRNe protection solutions, or used as a standalone device in building security and mail screening applications.

In addition to the standalone BioFlash device, we also offer a MailGuard System that includes a negative pressure hood for large-batch mail screening. Check out our mail screening application page for more information. 


Used by the US Government for 8+ years


Rapid results in under 2 minutes


Onsite evaluations available


Best-in-class biothreat detection

PathSensors will design a custom system tailored to your building and detection requirements

Step-by-step customized implementation:

PathSensors provides a comprehensive evaluation of your facility to determine the best building protection solution. Our talented team of engineers and developers will work with you to install a BioFlash system that fits your needs. 

Multiple options for implementation: 

PathSensors will help you determine which method of implementation  is best for you: point testing, networked testing, triggered testing, or a customized design.

Point Testing

Sampling of air in highly sensitive locations

Networked Testing

Sampling of air through the building’s HVAC system, providing active environment-sensing protection.

Triggered Testing

Particle detectors continuously monitor the space. When particle levels rise, an identification test for that air space is initiated. 

Take a look at our BioFlash video to learn more:

Technology You Can Count On

Both the BioFlash and the Zephyr use CANARY® (Cellular Analysis and Notification of Antigen Risks and Yields) technology. This novel detection technology, developed at MIT-Lincoln Laboratory, utilizes cells that have been modified to express antibodies on their cell surfaces against targets of choice, as well as to express the bioluminescent protein aequorin – which we sourced from jellyfish!

Aequorin emits light when exposed to the increases in intracellular calcium levels that occur when the biosensor interacts with the pathogens. Basically, the biosensor cells light up like a glowstick if a threat is detected, which allows our machines to give you fast, accurate results at the speed of light. 

Due to the rapid kinetics and signal amplification of cell-based signaling, detection of pathogens with CANARY® offers sensitivities down to 50 cfu/pfu with a 5 minute time to result. What does this mean? Our technology is faster and more sensitive than the competition, period. Sophisticated algorithms are then used to accurately detect and identify pathogens based on the biosensor light emission, so that you can keep yourself, your employees, and your products safe.

CANARY is trusted and tested by the U.S. Department of Defense

“[PathSensors] went above and beyond with its customer service by regularly inquiring as to [our] satisfaction with its product and services… the products arrived in excellent condition and performed at a consistently high level.”

- US Government Biodefense Customer


CANARY® technology has been tested at Dugway Proving Ground, Edgewood Chemical and Biological Center, Battelle Memorial Labs, and Pacific Northwest National Labs. The technology has been validated through its use in a government building security biomonitoring system.

CANARY® biosensors offer a superior level of speed and sensitivity. PathSensors has a selection of reagents for the most common biothreat agents including:

Third-party testing and validations

Our bioflash detection system provides unparalleled speed and sensitivity, allowing you to identify pathogens in your building or mailroom at the speed of light. The technology, CANARY, has undergone extensive third-party testing and was determined by Pacific Northwest National Labs (PNNL) to be 10,000 times as sensitive as other competing immunoassays. To see more results by external labs, visit our validations page. 

Protect you and your employees from airborne threats

Interested in working with us? 

Get In Touch

701 E Pratt Street
Baltimore, MD 21202

Phone: 443.557.6150


About PathSensors

At PathSensors we are committed to making the world a safer place. We are always excited to tackle new challenges, so please contact us to discuss collaborations or development projects.