Biodefense

CANARY® assays to detect harmful pathogens and keep you safe

Building Protection & Mail Screening


Incorporating CANARY® technology, the BioFlash Pathogen Identifier provides rapid, sensitive and specific identification of biothreat agents (bacteria, viruses and toxins) from aerosol samples. The BioFlash can be integrated into a suite of CBRNe protection solutions, or used as a standalone device in building security and mail screening applications.

Biothreat Response


The Zephyr Pathogen Identifier is a modular instrument system that can be deployed to respond to biothreat events in the field. Available in bench top, rackmount and mobile configurations, the Zephyr offers clear results in as few as 5 minutes, with levels of detection comparable to the most sophisticated lab-based tests.

Technology You Can Count On

Both the BioFlash and the Zephyr use CANARY® (Cellular Analysis and Notification of Antigen Risks and Yields) technology. This novel detection technology, developed at MIT-Lincoln Laboratory. CANARY® utilizes B lymphocyte cells that have been modified to express antibodies on their cell surfaces against targets of choice, as well as to express the bioluminescent protein aequorin. Aequorin emits light when exposed to the increases in intracellular calcium levels that occur upon interaction of the biosensor’s antibody with its cognate target. Due to the rapid kinetics and signal amplification of cell-based signaling, detection of pathogens with CANARY® offers sensitivities down to 50 cfu/pfu with a 5 minute time to result. Sophisticated algorithms are used to accurately detect and identify pathogens based on the biosensor light emission.

CANARY ® technology has been tested at Dugway Proving Ground, Edgewood Chemical and Biological Center and Battelle Memorial Labs. The technology has been validated through its use in a government building security biomonitoring system.

CANARY® biosensors offer a superior level of speed and sensitivity. PathSensors has a selection of reagents for the most common biothreat agents including:

  • Bacillius anthracis (anthrax)
  • Ricin
  • Botulism
  • Yersinia pestis (black plague)
  • Tularemia
  • Orthopox virus (smallpox)